Методы биологического исследования, экспериментальные приёмы и оборудование для изучения живых организмов.


177 публикаций

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Flaxseed protein-derived sulfhydryl peptides mitigate cardiac damage induced by lead exposure through lead chelation and modulation of gut microbiota
Biofilm-mediated antibiotic cross-protection: <i>Acinetobacter baumannii</i> -driven enhancement of <i>Elizabethkingia anopheles</i>
Machine learning application in molecular science research field
Selective interaction of SMCHD1 with chromatin is governed by LRIF1 and SMCHD1 ATPase activity
Comparative osteogenic performance of Chinese hamster ovary cell-derived versus <i>Escherichia coli</i> -derived recombinant human bone morphogenetic protein-2
Diosmetin Modulates EMT-Associated Plasticity and Fibroblast-Activation Markers in Parallel Breast Cancer In Vitro Models
Surface Engineering of Zirconia Implants: Current Options and Innovations
GLUT9b- and ABCG2-mediated collecting duct urate transport uncover a vasopressin-independent mechanism of renal water reabsorption
Murine model of high bone mass osteogenesis imperfecta exhibits bone matrix hyper-mineralization, misaligned mineral crystals, and altered osteoblast differentiation
Integrating machine learning-based molecular design with experimental validation for the discovery of EGFR inhibitors in lung cancer
Transposable element dynamics drive rapid evolution of centromere architecture in the Avena genus
Mandibular Periosteal Cells Exhibit Trpv2-Dependent Mechanosensitivity to Microscale Stiffness Patterns
Antibiotic exposure and recovery of persister states influence virulence phenotypes in Pseudomonas aeruginosa
Low-Intensity Pulsed Ultrasound Enhances Intramembranous Bone Healing in a Critical-Size Bone Defect of the Rat Calvaria
<i>A</i> ntimicrobial activity and phytochemical profile of <i>Rumex nervosus</i> extracts
Mass spectrometry proteomics for studying mitostasis
Long-term ovarian function risks associated with combined oral contraceptive administration in polycystic ovary syndrome: multisource data integration and protective mechanisms of metformin
Phocaeicola vulgatus improves anxiety-like behavior by ameliorating amygdala neuroinflammation and the neurite impairment in IBS
Amyloid-beta fibrils as active contributors to synaptic dysfunction in Alzheimer’s disease
Integrative bulk and single-cell transcriptome analyses reveals manganese metabolism-related prognostic genes in clear cell renal cell carcinoma with experimental validation
Reversing the Fold: Polyanionic Macrocycle Dissolves αA66–80 Crystallin Peptide Aggregates
Toward a world model for corrosion science
Protective effect of betanin on liver injury after jejunal ischemia-reperfusion injury
Molecular mechanisms, clinical phenotypes, and advances in Huntington’s disease therapeutics
Unraveling the mechanism of action of the PepGAT peptide against Candida albicans through proteomics approaches
Artificial intelligence in 3D bioprinting and biofabrication: a validation-stringency assessment
Integrating imaging and mathematical modeling to predict and optimize patient outcomes in oncology
Focused ultrasound-induced cavitation in a human brain microphysiological system produces injury signaling biomarkers consistent with blast trauma
Melatonin alleviates mitochondrial damage by regulating SIRT3‑mediated mitochondrial dynamics in granulosa cells under PCOS‑like conditions
Development of a production strategy based on the modification of metabolic regulation processes in Pichia pastoris.
A one-tube RT-RPA–CRISPR/Cas12a system for zoonotic virus detection
MRPL3 enhances mitochondrial function via the TOMM40/PGC-1α/TFAM axis to drive early recurrence in hepatocellular carcinoma
Decoding Animal Skin for Engineering: Mechanical Function, Morphology, and Emerging Bioinspired Applications
Spider venom peptides Ht1a and Gg1a are toxic to honeybee parasite <i>Varroa destructor</i> by topical application.
ОСОБЕННОСТИ НЕВМЕНЯЕМОСТИ В УГОЛОВНОМ ЗАКОНОДАТЕЛЬСТВЕ ЗАРУБЕЖНЫХ СТРАН
ПОЛУЧЕНИЕ УРЕТАНОВОГО ПОКРЫТИЯ НОВОГО ПОКОЛЕНИЯ
Benchmarking urinary cell transcriptomes for noninvasive differentiation of BK polyomavirus–associated nephropathy from T cell–mediated rejection
Bone regeneration: current concepts and future directions
Structural dynamics of the π-stacking network governing cofactor-substrate cooperativity of SbSOMT methyltransferase
The Systematic Study of Spatially Conserved Salt Bridges in Protein
Mechanical interactions govern self-organized ordering in bacterial colonies on surfaces
Current issues in research on structure–property relationships in polymer nanocomposites
Discovery of BEND4 as a novel single-gene prognostic marker and therapeutic target for adverse AML
Complete genomes reveal a refined map of Mycobacterium tuberculosis genetic diversity across evolutionary scales
Avidity-by-design: spatial control of T7 peptide presentation on polymersomes dictates blood-brain barrier transport fate
Development and validation of pathomics signature for predicting prognosis of advanced high-grade serous ovarian carcinoma patients after platinum-based chemotherapy
Mathematical and computational modeling of biosystems at different levels of organization
3D chromatin architecture in cancer: mechanisms of dysregulation and emerging therapeutic strategies
Chromatin insulators homie and nhomie can interact with distant copies either together or separately, with distinct outcomes for enhancer-promoter interactions
Linalool exhibits potent antibacterial and anti-biofilm activity against carbapenem-resistant Acinetobacter baumannii
Disrupting phage liquid crystalline droplets restores antibiotic susceptibility in Pseudomonas aeruginosa biofilms
HIV-1 BG505 SOSIP immunization induced B cell expansion targeting the 465-glycan hole, with neutralizing antibodies exhibiting distinct binding modes and mechanisms of virus inhibition
Cytotoxic CD39 <sup>+</sup> tumor-associated NK cells respond to NKG2A blockade in lung cancer
Философский анализ техники и философия диалога
ЗНАЧЕНИЕ БИОЛОГИИ В ПРОФЕССИИ ТЕХНИКА ПО ОБСЛУЖИВАНИЮ АВТОМОБИЛЕЙ
Chimeric 3D model of EGFR and VEGFR-2 for the discovery of dual inhibitors
Lactiplantibacillus plantarum-inoculated silage improves milk fat in dairy goats by reprogramming rumen microbiota to promote pyruvate metabolism
Effect of different carbon allotropes for electrochemical glucose detection
Silicone oil tamponade in vitreoretinal surgery and future perspective: a narrative review
Comprehensive proteogenomic characterization reveals clinically relevant molecular subtypes associated with medulloblastoma progression
3119-LB: Generation of a GLP1R-Knockdown EndoC-ßH5 Model to Elucidate Dual Incretin Signaling Mechanisms
Lonp1 expression and correlation with mitophagy and immune infiltration markers in colon adenocarcinoma.
МОДЕЛЮВАННЯ КРОВОТОКУ З ОБЕРТАННЯМ ЧЕРЕЗ ПРУЖНО-АКТИВНІ СУДИНИ АРТЕРІАЛЬНОЇ СИСТЕМИ КРОВООБІГУ ЛЮДИНИ
Mechanisms of inflammatory response in secondary brain injury: a review of computational approaches, challenges, and future directions
NbBayesLM: bayesian prediction of nanobody thermostability using protein language model
In vivo dynamic hotspot-enhanced Raman spectroscopy via reconfigurable swarming nanoprobes
DNA Data Storage: A Critical Review of Bio-Algorithmic Integration, Performance-Cost Tradeoffs, and Future Directions for Scalable Architectures
DNA-intercalating antiphage molecules trigger abortive infection through mutual destruction and synergize with bacterial immunity
Dose-dependent hormone actions at estrogen receptor enhancers specify distinct molecular and biological outcomes
Same-day tagmentation PCR-based whole genome sequencing of bacteriophage genomes from a single plaque without DNA extraction
Facile and cost-effective synthesis and characterization of hormone stabilized biocompatible gold nanoparticles for biomedical applications
Preparation and characterization of self-healing nanocomposite hydrogels based on chitosan/polyethylene glycol/bacterial nanocellulose for wound dressing applications
Integration of gene expression analysis and molecular docking in revealing stress-responsive functions of potato chitinases
Mechanisms underlying the age-related changes in muscle contractile properties
Beyond networks: Functional connectivity as eigenmode resonance
Mechanobiology of solid tumor vasculature: implications for tumor progression
Cyanine-modified ssODNs enhance CRISPR-Cas9 HDR in stem cell embryo models via chromatin and chemical modulation
Site-Specific Raman Probes Reveal Droplet Aging and Residue-Level Fibril Polymorphism in TDP-43 <sub>CTD</sub>
Advancements in characterization of protein dynamics with machine learning
Biological pathways related to mirna-125a-5p in behavioral variant of frontotemporal dementia
PEBP4 alleviates muscle wasting in lung cancer cachexia via KEAP1–NRF2-mediated redox homeostasis
Solution NMR study of the titin I-band IgI domain I82 shows unusual conformational dynamics
Effect of acute ischemic stroke in 3xTg-AD mouse model of Alzheimer’s disease
Biosensors as transformative tools for multiplex detection of respiratory viral pathogens
BIOLOGICAL ACTIVITY OF RECOMBINANT IFN-γ FROM LARGEMOUTH BASS (MICROPTERUS SALMOIDES) AND ITS PROTECTIVE MECHANISM AGAINST LMBV INFECTION
Global research landscape and hotspots for endoplasmic reticulum stress in Glioma: from 2000 to 2024 – a bibliometric analysis
Characterization of Metformin-Associated Metabolic Gene Expression Alterations in Type 2 Diabetes: Evidence from Patient Blood Samples and HepG2 Cells
Streptococcus-derived CpsA–CpsC fusion protein induces apoptosis in cervical cancer cells through in silico and in vitro methods
Profiling Nucleolin Phosphorylation during DNA Damage Response and Cell Cycle Arrest
The Interactions Between Bacteria, Platelets Bags and Platelets
Host–Pathogen Dual Targeting With Repurposed Drugs Identifies a Synergistic Therapy for Intracellular <i>Staphylococcus aureus</i>
Molecular prevalence, genomic characterization, and zoonotic potential of novel paramyxovirus and hepacivirus in Alexandromys fortis, Republic of Korea
High-Yield Expression, Enhanced Stability, and Broad-Spectrum Substrate Catalysis of the Short-Chain Fungal Unspecify Peroxygenase from <i>Thermoascus thermophilus</i>
Feedforward compensation of piezo nonlinearity for high-precision high-speed atomic force microscopy
6-Shogaol inhibits HSCs activation and liver fibrosis by regulating glycolytic reprogramming via targeting HIF-1α
Quantum dot biosensors for highly sensitive and multiplex detection in biomedical diagnostics
Consensus statement from the second RdRp Summit: towards a unified framework for RNA virus biology
From Cell Line to Fillet: A Review of Biological and Engineering Strategies in Cultivated Seafood
Converging chemistry and clinical orthopedics in the emerging role of MOFs in advanced bone defect repair
Computational models in directed cell migration
Small extracellular vesicle signaling and mitochondrial transfer reprogram T helper cell function in human asthma
Single-cell transcriptomics and mouse model phenotyping for biomarker screen of peripheral blood in Huntington’s disease
Estimation of protein melting temperatures using small-ladder replica exchange simulations
Enzymatic Encoding of Topology in an Intrinsically Disordered Single‐Chain Protein
К юбилею журнала «Историко-биологические исследования»
Тактические аспекты и технико-криминалистическое обеспечение работы со следами биологического происхождения при производстве осмотра места происшествия
Технико-юридический анализ норм законодательства в сфере обращения лекарственных средств, медицинских изделий и биологически активных добавок
Особенности профессиональной подготовки иностранных специалистов в медицинском вузе
Anticancer effects of bisabolol oxide A-Loaded Micellar/Liposomal nanoparticles on DU-145 cells with deregulation of miR-34a and miR-181a: in silico and in vitro studies
Evaluation of an experimental model of senescence SAMR1/SAMP8 for microRNA studies in acute myocardial infarction: role of sex and aging
Thermodynamic entropy management in human motor control across circadian and thermal challenges
Decellularization of porcine small-diameter vascular grafts: evaluation of a latrunculin B-based method and novel perfusion approach
Hypoxia, metastatic origin and HPV16 E6/E7 expression differentially shape the radiation response in head and neck squamous cell carcinoma cell lines
<em>In silico</em> exploration of structural peculiarities of heme-binding proteins
Identification and analysis of oxidative stress-related genes associated with the occurrence and development of diabetic retinopathy
From fatal disease to functional cure: 25 years of tyrosine kinase inhibition in chronic myeloid leukemia
Light- and chemical-induced ciliary signaling governs dorsal/ventral regionalization of human telencephalic organoids
Bioconductor: open software development for computational biology and bioinformatics
Sieve elements. Hidden corners, fierce debates, future prospects
Natural polymorphisms in the bovine leukemia virus microRNA cluster modulate miRNA expression and host regulatory pathways
FlowMol3: flow matching for 3D <i>de novo</i> small-molecule generation.
Atg18 interaction positions Atg2 for efficient lipid transfer into phagophore elongation
Muscle-specific differences in MyHC isoform abundance, metabolic profile and gene expression in cattle
A single-cell RNA sequencing dataset of cardiac aging in African Turquoise Killifish
Hsa-circ_0081481-miR 3960-FBXO24 regulatory axis in non-obstructive azoospermia identifies potential biomarkers of spermatogenic failure
Hierarchical multi-timescale structural dynamics of the disordered N-terminal of p53
Volume electron microscopy reveals bacterial endosymbiosis within host mitochondria
Copper-Zinc Superoxide Dismutase (SOD1) Is Released by Microglial Cells and Confers Neuroprotection against 6-OHDA Neurotoxicity
CHARMM: The biomolecular simulation program
ColabFold: making protein folding accessible to all
SWISS-MODEL: homology modelling of protein structures and complexes
Hydrophobic interaction chromatography resolves extracellular vesicle fractions with distinct lipidomic signatures
Carbon halogen bond dissociation energy predictions through automated machine learning pipeline
GSK-3 regulates CD4-CD8 cooperation for super-armed CD8+ cytolytic T cells in immunotherapy against tumors
GROMACS 4:  Algorithms for Highly Efficient, Load-Balanced, and Scalable Molecular Simulation
STRING v11: protein–protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasets
Initial sequencing and analysis of the human genome
Pfam: the protein families database
Integrative analysis of 111 reference human epigenomes
DNA methylation patterns and epigenetic memory
Height Loss and Intervertebral Disc Compression as the Macroscopic 3D→2D Transition: A Statistical Physics Framework for ACF Collapse in the Human Axial Column
Height Loss and Intervertebral Disc Compression as the Macroscopic 3D→2D Transition: A Statistical Physics Framework for ACF Collapse in the Human Axial Column
The Channelled Substrate: Physical Constraints on Biological Variation
The Channelled Substrate: Physical Constraints on Biological Variation
Deformable Medical Image Registration: A Survey
Biology of Bone Tissue: Structure, Function, and Factors That Influence Bone Cells
Active Particles in Complex and Crowded Environments
Advancing The Cancer Genome Atlas glioma MRI collections with expert segmentation labels and radiomic features
Understanding the Role of Physics-Informed Inductive Biases in Brain Tumor Segmentation: A Theoretical and Methodological Perspective
Cuticular Hydrocarbon Composition of Adhesive Secretions from Functionally Different Attachment Pads of the Stick Insect Medauroidea extradentata (Phasmatodea)
Toward a Bioelectric Systems Theory of Chronic Disease: A Mechanistic and Philosophical Analysis of Insulin ResistanceA Theoretical Investigation at the Intersection of Biophysics, Biochemistry, and Philosophy of Medicine
Investigation of Red Blood Cell Properties on Impedance Signatures Generated in a Coulter Counter
Early Post‑Traumatic Osteoarthritis Features Greater Cartilage Extracellular Matrix Proteoglycan Loss Compared to the Pericellular Matrix
Differential prognostic value of circulating biomarkers across small ischemic stroke subtypes
Recurrent structural variation and recent turnover at the 17q21.31 locus in humans and great apes
Molecular Dynamics Studies on Epitope-Resolved Structural Dynamics and Energetics of Japanese Cedar Cry j 1 Allergen Adsorption onto PET Microplastics
Multiscale biomechanics-driven design pipelines for reconstructive bone scaffolds
Mechanics-Driven Emergence of Mesenchymal Migration Features
Piezo2-Initiated Ultrafast Signaling and Its Acquired Channelopathy in Light of Quantum Gravity Theory
Improving tree stability with optimized pruning: a comprehensive cycle method
Exploring the mechanical heterogeneity of human adipose-derived mesenchymal stem cells: A pilot study
Molecular regulators of regeneration and strategies for overcoming genotype-dependent recalcitrance in wheat (Triticum aestivum)
Synthesis and anti-antileishmanial profile of novel thiazolidine-4-one derivatives and molecular docking and molecular dynamics simulations studies
Genome assemblies of the liverwort Blasia pusilla uncover a well-defined pseudoautosomal region on homomorphic UV sex chromosomes
Advances in Polydopamine-Based Nanoplatforms: Antioxidant Mechanisms and Applications in Oxidative Stress-Mediated Diseases
Single-cell profiling and machine learning identify cuproptosis-related fibroblast subpopulations and fibrogenesis modulator AEBP1 in endometriosis
Supramolecular Assembly in Short Peptide Systems for Selective Metabolite Recognition and Drug Nanoencapsulation
Wearable and Stretchable Strain Sensors: Materials, Sensing Mechanisms, and Applications
Hierarchical Structure and Nanomechanics of Collagen Microfibrils from the Atomistic Scale Up
Microtubules can bear enhanced compressive loads in living cells because of lateral reinforcement
Moving beyond the glial scar for spinal cord repair
Atomic force microscopy-based mechanobiology
Leaf venation: structure, function, development, evolution, ecology and applications in the past, present and future
Imaging and cancer: A review
Joint Optimization of Radio and Computational Resources for Multicell Mobile-Edge Computing
Mechanics, malignancy, and metastasis: The force journey of a tumor cell
Current hydrogel advances in physicochemical and biological response-driven biomedical application diversity